Menovair

Ingredient Research

Red Clover

Red Clover

Compared with placebo, red clover isoflavone supplementation in postmenopausal women significantly decreased menopausal symptoms and had a positive effect on vaginal cytology and triglyceride levels.

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Hidalgo LA, Chedraui PA, Morocho N, Ross S, San Miguel G. Gynecol Endocrinol. 2005 Nov;21(5):257-64.

Ghazanfarpour M, Sadeghi R, Roudsari RL, Khorsand I, Khadivzadeh T, Muoio B. J Obstet Gynaecol. 2016;36(3):301-11.

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Ghazanfarpour M, Sadeghi R, Latifnejad Roudsari R, Mirzaii Najmabadi K, Mousavi Bazaz M, Abdolahian S, Khadivzadeh T. Avicenna J Phytomed. 2015 Nov-Dec;5(6):498-511.

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Kim MR, Kim HJ, Yu SH, Lee BS, Jeon SY, Lee JJ, Lee YC. Evid Based Complement Alternat Med. 2020 May 23;2020:7941391.

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Lambert MNT, Thorup AC, Hansen ESS, Jeppesen PB. PLoS One. 2017 Jun 7;12(6):e0176590.

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van de Weijer PH, Barentsen R. Maturitas. 2002 Jul 25;42(3):187-93.

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Black Cohosh

Black Cohosh

The [Greene climacteric scale (GCS)] total score in the treatment group was significantly lower than that in the control group. [...] The treatment group showed significantly more improvement than the control group in all GCS subscale scores (vasomotor, psychiatric, physical, and sexual symptoms; secondary outcomes). The differences between the treatment and control groups at week 8 were significantly higher [...] than those at week 4 in terms of the total scores and the vasomotor and psychiatric subscale scores.

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Mohammad-Alizadeh-Charandabi S, Shahnazi M, Nahaee J, Bayatipayan S. Chin Med. 2013 Nov 1;8(1):20.

Mehrpooya M, Rabiee S, Larki-Harchegani A, Fallahian AM, Moradi A, Ataei S, Javad MT. J Educ Health Promot. 2018 Mar 1;7:36.

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Uebelhack R, Blohmer JU, Graubaum HJ, Busch R, Gruenwald J, Wernecke KD. Obstet Gynecol. 2006 Feb;107(2 Pt 1):247-55.

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McKenna DJ, Jones K, Humphrey S, Hughes K. Altern Ther Health Med. 2001 May-Jun;7(3):93-100.

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Ruhlen RL, Sun GY, Sauter ER. Integr Med Insights. 2008;3:21-32.

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Shahnazi M, Nahaee J, Mohammad-Alizadeh-Charandabi S, Bayatipayan S. J Caring Sci. 2013 Jun 1;2(2):105-13.

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Shayan A, Masoumi SZ, Kazemi F, Oshvandi K. J Menopausal Med. 2020 Aug;26(2):135-142.

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Dong Quai

Dong Quai

The estrogenic activity of a commercial standardized extract of the roots of Angelica sinensis, used to relieve climacteric symptoms was evaluated using in vivo tests [...] The results obtained have shown that the administration of a standardized ethanol extract [...] exhibited a stimulation of the uterine histoarchitecture, a significant cornification in the vaginal epithelium and a reduction of serum LH concentration showing the estrogenic nature of the extract.

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Circosta C, Pasquale RD, Palumbo DR, Samperi S, Occhiuto F. Phytother Res. 2006 Aug;20(8):665-9.

Hao Q, Wang J, Niu J, Zhao P, Cui Y, Sun L, Xue X. Zhongguo Zhong Yao Za Zhi. 2009 Mar;34(5):620-4.

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Lim DW, Kim YT. Nutrients. 2014 Oct 16;6(10):4362-72.

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Wu YC, Hsieh CL. Chin Med. 2011 Aug 25;6:32.

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Du J, Bai B, Kuang X, Yu Y, Wang C, Ke Y, Xu Y, Tzang AH, Qian ZM. J Ethnopharmacol. 2006 Nov 3;108(1):54-8.

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Chasteberry

Chasteberry

Menopausal symptoms were assessed using the Greene Scale before and 8 weeks after the intervention. [...] After the intervention, the mean scores for total menopausal disorder, anxiety, and vasomotor dysfunction were significantly lower in the Vitex group than in the placebo group.

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Naseri R, Farnia V, Yazdchi K, Alikhani M, Basanj B, Salemi S. Korean J Fam Med. 2019 Nov;40(6):362-367.

Ibrahim NA, Shalaby AS, Farag RS, Elbaroty GS, Nofal SM, Hassan EM. Nat Prod Res. 2008 Apr 15;22(6):537-46.

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Toh MF, Sohn J, Chen SN, Yao P, Bolton JL, Burdette JE. Steroids. 2012 Jun;77(7):765-73.

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Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Phytomedicine. 2004 Jan;11(1):18-23.

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Lucks BC, Sørensen J, Veal L. Complement Ther Nurs Midwifery. 2002 Aug;8(3):148-54.

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Chopin Lucks B. Complement Ther Nurs Midwifery. 2003 Aug;9(3):157-60.

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Licorice Root

Licorice Root

The frequency of hot flash decreased significantly in the [licorice group] and this lasted for 2 weeks after the administration of the capsules. The severity of hot flash decreased in the licorice group as well. [...] Recurrence of frequency and severity of hot flashes occurred 2 weeks after the termination of therapy.

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Nahidi F, Zare E, Mojab F, Alavi-Majd H. Iran J Pharm Res. 2012 Spring;11(2):541-8.

Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. Health Care Women Int. 2014 Jan;35(1):87-99.

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Hajirahimkhan A, Simmler C, Yuan Y, Anderson JR, Chen SN, Nikolić D, Dietz BM, Pauli GF, van Breemen RB, Bolton JL. PLoS One. 2013 Jul 12;8(7):e67947.

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Boonmuen N, Gong P, Ali Z, Chittiboyina AG, Khan I, Doerge DR, Helferich WG, Carlson KE, Martin T, Piyachaturawat P, Katzenellenbogen JA, Katzenellenbogen BS. Steroids. 2016 Jan;105:42-9.

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Tanideh N, Zareian Z, Hosseinpour R, Tanideh R, Koohpeyma F, Koohi-Hosseinabadi O, Shekarkhar G, Irajie C, Taghi MM, Barhaghtalab MJY, Iraji A. Biomed Res Int. 2022 Aug 10;2022:7879432.

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