Glucoven Ingredient Research

Alpha Lipoic Acid

Alpha Lipoic Acid

"The current study demonstrated that [alpha lipoic acid] enhances hepatic [metabolic hormone] sensitivity and prevents the development of NAFLD; furthermore, ALA ameliorates glucose metabolism by modulating the [metabolic-hormone-signaling] pathway. Overall, ALA facilitates the liver's capacity for glucose production and glucose utilization and might be effective in decreasing whole-body glucose catabolism."

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Yi Yang, Wang Li, Yang Liu, Yan Li, Ling Gao, and Jia-jun Zhao. Acta Pharmacol Sin. 2014 Oct; 35(10): 1285–1292.

Kamenova P.

Hormones (Athens). 2006;5(4):251-258. doi:10.14310/horm.2002.11191

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Ansar H, Mazloom Z, Kazemi F, Hejazi N.

Saudi Med J. 2011;32(6):584-588.

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Singh U, Jialal I.

Nutr Rev. 2008 Nov; 66(11): 646–657.

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Jacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ, Dietze GJ, Henriksen EJ.

Diabetes. 1996;45(8):1024-1029. doi:10.2337/diab.45.8.1024

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Salehi B, Berkay Yılmaz Y, Antika G, Boyunegmez Tumer T, Fawzi Mahomoodally M, Lobine D, Akram M, Riaz M, Capanoglu E, Sharopov F, Martins N, Cho WC, Sharifi-Rad J

Biomolecules. 2019 Aug; 9(8): 356.

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Cinnamon

Cinnamon

"In tests of [metabolic hormone] activity [...], cinnamon extracts produced the greatest enhancement of glucose utilization of all the forty-nine herb, spice, and medicinal plant extracts tested. Subsequently, [...] cinnamon [was] found to increase [metabolic hormone] activity by approximately twenty-fold in the same assay."

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Anderson RA, Zhan Z, Luo R, Guo X, Guo Q, Zhou J, Kong J, Davis PA, Stoecker BJ. J Tradit Complement Med. 2016 Oct; 6(4): 332–336.

Qin B, Panickar KS, Anderson RA.

J Diabetes Sci Technol. 2010 May; 4(3): 685–693.

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Sartorius T, Peter A, Schulz N, Drescher A, Bergheim I, Machann J, Schick F, Siegel-Axel D, Schürmann A, Weigert C, Häring HU, Hennige AM.

PLoS One. 2014; 9(3): e92358.

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Allen RW, Schwartzman E, Baker WL, Coleman CI, Phung OJ.

Ann Fam Med. 2013;11(5):452-459. doi:10.1370/afm.1517

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Zare R, Nadjarzadeh A, Zarshenas MM, Shams M, Heydari M.

Clin Nutr. 2019;38(2):549-556. doi:10.1016/j.clnu.2018.03.003

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Medagama AB.

Nutr J. 2015; 14: 108.

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Berberine

Berberine

"Berberine acted by lowering fasting blood glucose and postprandial blood glucose from 1 week to the end of the trial. [...] Fasting plasma [metabolic hormone] and homeostasis model assessment of [metabolic hormone] resistance index were reduced by 28.1% and 44.7% (P<.001), respectively."

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Yin J, Xing H, Ye J. Metabolism. 2008;57(5):712-717. doi:10.1016/j.metabol.2008.01.013

Zhang H, Wei J, Xue R, et al.

Metabolism. 2010;59(2):285-292. doi:10.1016/j.metabol.2009.07.029

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Yin J, Xing H, Ye J.

Metabolism. 2008 May; 57(5): 712–717.

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Cao C, Su M.

Exp Ther Med. 2019 Apr; 17(4): 3009–3014.

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Yang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M.

Evid Based Complement Alternat Med. 2012; 2012: 363845.

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Geng FH, Li GH, Zhang X, Zhang P, Dong MQ, Zhao ZJ, Zhang Y, Dong L, Gao F.

Br J Pharmacol. 2016 May; 173(10): 1569–1579.

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Bitter Melon

Bitter Melon

"[Bitter melon] greatly enhanced [metabolic hormone] sensitivity, reversed liver steatosis, reduced body-fat mass. [...] This study suggested that the favorable effects of BME on increasing [metabolic hormone] sensitivity and attenuating hepatic steatosis may be attributed to the mediation of SIRT1 and AMPK-ACC signaling."

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Yoon NA, Park J, Lee J, Jeong JY, Kim HK, Lee HS, Hwang IG, Roh GS, Kim HJ, Cho GJ, Choi WS, Lee DH, Kang SS. Dev Reprod. 2017 Sep; 21(3): 259–267.

Mahwish, Saeed F, Arshad MS, Nisa MU, Nadeem MT, Arshad MU.

Lipids Health Dis. 2017; 16: 211.

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Hsu PK, Pan FFC, Hsieh CS.

Nutrients. 2020 May; 12(5): 1252.

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Hartajanie L, Fatimah-Muis S, Heri-Nugroho Hs K, Riwanto I, Sulchan M.

J Nutr Metab. 2020; 2020: 6369873.

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J Ethnopharmacol. 2018;216:1-7. doi:10.1016/j.jep.2018.01.016

Krawinkel MB, Ludwig C, Swai ME, Yang RY, Chun KP, Habicht SD.

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Joseph B, Jini D.

Asian Pac J Trop Dis. 2013 Apr; 3(2): 93–102.

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Chromium

Chromium

"Significant differences in the fasting blood level of glucose compared to the baseline (190 mg/dL vs 150 mg/dL, p < 0.001) were found at the end of the study. [...] We conclude that [...] dietary supplementation with chromium is beneficial in moderating glucose intolerance."

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Rabinovitz H, Friedensohn A, Leibovitz A, Gabay G, Rocas C, Habot B. Int J Vitam Nutr Res. 2004;74(3):178-182. doi:10.1024/0300-9831.74.3.178

Zhang W, Chen H, Ding Y, Xiang Q, Zhao J, Feng W, Yang L.

Indian J Pharmacol. 2020 Jan-Feb; 52(1): 31–38.

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Sharma S, Agrawal RP, Choudhary M, Jain S, Goyal S, Agarwal V.

J Trace Elem Med Biol. 2011;25(3):149-153. doi:10.1016/j.jtemb.2011.03.003

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Ngala RA, Awe MA, Nsiah P.

PLoS One. 2018; 13(7): e0197977.

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Chen WY, Chen CJ, Liu CH, Mao FC.

Diabetes Obes Metab. 2009;11(4):293-303. doi:10.1111/j.1463-1326.2008.00936.x

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