Ingredient Research
Alpha Lipoic Acid
Alpha Lipoic Acid
The current study demonstrated that [alpha lipoic acid] enhances hepatic [metabolic hormone] sensitivity and prevents the development of NAFLD; furthermore, ALA ameliorates glucose metabolism by modulating the [metabolic-hormone-signaling] pathway. Overall, ALA facilitates the liver's capacity for glucose production and glucose utilization and might be effective in decreasing whole-body glucose catabolism.
Read the Abstract
Kamenova P. Hormones (Athens). 2006;5(4):251-258. doi:10.14310/horm.2002.11191
Read the AbstractAnsar H, Mazloom Z, Kazemi F, Hejazi N. Saudi Med J. 2011;32(6):584-588.
Read the AbstractSingh U, Jialal I. Nutr Rev. 2008 Nov; 66(11): 646–657.
Read the AbstractJacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ, Dietze GJ, Henriksen EJ. Diabetes. 1996;45(8):1024-1029. doi:10.2337/diab.45.8.1024
Read the AbstractSalehi B, Berkay Yılmaz Y, Antika G, Boyunegmez Tumer T, Fawzi Mahomoodally M, Lobine D, Akram M, Riaz M, Capanoglu E, Sharopov F, Martins N, Cho WC, Sharifi-Rad J. Biomolecules. 2019 Aug; 9(8): 356.
Read the AbstractCinnamon
Cinnamon
In tests of [metabolic hormone] activity [...], cinnamon extracts produced the greatest enhancement of glucose utilization of all the forty-nine herb, spice, and medicinal plant extracts tested. Subsequently, [...] cinnamon [was] found to increase [metabolic hormone] activity by approximately twenty-fold in the same assay.
Read the Abstract
Qin B, Panickar KS, Anderson RA. J Diabetes Sci Technol. 2010 May; 4(3): 685–693.
Read the AbstractSartorius T, Peter A, Schulz N, Drescher A, Bergheim I, Machann J, Schick F, Siegel-Axel D, Schürmann A, Weigert C, Häring HU, Hennige AM. PLoS One. 2014; 9(3): e92358.
Read the AbstractAllen RW, Schwartzman E, Baker WL, Coleman CI, Phung OJ. Ann Fam Med. 2013;11(5):452-459. doi:10.1370/afm.1517
Read the AbstractZare R, Nadjarzadeh A, Zarshenas MM, Shams M, Heydari M. Clin Nutr. 2019;38(2):549-556. doi:10.1016/j.clnu.2018.03.003
Read the AbstractMedagama AB. Nutr J. 2015; 14: 108.
Read the AbstractBerberine
Berberine
Berberine acted by lowering fasting blood glucose and postprandial blood glucose from 1 week to the end of the trial. [...] Fasting plasma [metabolic hormone] and homeostasis model assessment of [metabolic hormone] resistance index were reduced by 28.1% and 44.7% (P<.001), respectively.
Read the Abstract
Zhang H, Wei J, Xue R, et al. Metabolism. 2010;59(2):285-292. doi:10.1016/j.metabol.2009.07.029
Read the AbstractYin J, Xing H, Ye J. Metabolism. 2008 May; 57(5): 712–717.
Read the AbstractCao C, Su M. Exp Ther Med. 2019 Apr; 17(4): 3009–3014.
Read the AbstractYang J, Yin J, Gao H, Xu L, Wang Y, Xu L, Li M. Evid Based Complement Alternat Med. 2012; 2012: 363845.
Read the AbstractGeng FH, Li GH, Zhang X, Zhang P, Dong MQ, Zhao ZJ, Zhang Y, Dong L, Gao F. Br J Pharmacol. 2016 May; 173(10): 1569–1579.
Read the AbstractBitter Melon
Bitter Melon
[Bitter melon] greatly enhanced [metabolic hormone] sensitivity, reversed liver steatosis, reduced body-fat mass. [...] This study suggested that the favorable effects of BME on increasing [metabolic hormone] sensitivity and attenuating hepatic steatosis may be attributed to the mediation of SIRT1 and AMPK-ACC signaling.
Read the Abstract
Mahwish, Saeed F, Arshad MS, Nisa MU, Nadeem MT, Arshad MU. Lipids Health Dis. 2017; 16: 211.
Read the AbstractHsu PK, Pan FFC, Hsieh CS. Nutrients. 2020 May; 12(5): 1252.
Read the AbstractHartajanie L, Fatimah-Muis S, Heri-Nugroho Hs K, Riwanto I, Sulchan M. J Nutr Metab. 2020; 2020: 6369873.
Read the AbstractKrawinkel MB, Ludwig C, Swai ME, Yang RY, Chun KP, Habicht SD. J Ethnopharmacol. 2018;216:1-7. doi:10.1016/j.jep.2018.01.016
Read the AbstractJoseph B, Jini D. Asian Pac J Trop Dis. 2013 Apr; 3(2): 93–102.
Read the AbstractChromium
Chromium
Significant differences in the fasting blood level of glucose compared to the baseline (190 mg/dL vs 150 mg/dL, p < 0.001) were found at the end of the study. [...] We conclude that [...] dietary supplementation with chromium is beneficial in moderating glucose intolerance.
Read the Abstract
Zhang W, Chen H, Ding Y, Xiang Q, Zhao J, Feng W, Yang L. Indian J Pharmacol. 2020 Jan-Feb; 52(1): 31–38.
Read the AbstractSharma S, Agrawal RP, Choudhary M, Jain S, Goyal S, Agarwal V. J Trace Elem Med Biol. 2011;25(3):149-153. doi:10.1016/j.jtemb.2011.03.003
Read the AbstractNgala RA, Awe MA, Nsiah P. PLoS One. 2018; 13(7): e0197977.
Read the AbstractChen WY, Chen CJ, Liu CH, Mao FC. Diabetes Obes Metab. 2009;11(4):293-303. doi:10.1111/j.1463-1326.2008.00936.x
Read the Abstract