Frequently Asked Questions

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Yes. While results may vary, Princeton Consumer Research conducted a placebo-controlled study that confirmed 3Biome's effectiveness, and the results were statistically significant. After 30 days of use, more than 95% of participants reported more regular bowel movements, reduction in heartburn and indigestion, and less overall stomach upset. Click here for the complete results of the study.

We have designed 3Biome with smart probiotic cultures in a low-dose, high-efficiency capsule delivery system. In a placebo-controlled clinical study, more than 95% of participants found 3Biome helped improve digestion, reduce stomach upset, and normalize bowel movements within 30 days. Click here for the complete results of the study.

Each capsule of 3Biome is designed to build on the last to help fortify your gut microbiome with beneficial bacteria. We recommend waiting no more than 24 hours between doses to ensure optimal probiotic support for your gastrointestinal tract. Of course, everyone is different, and individual results may vary depending on your body type.

Yes, all of the above! Before formulation, each raw ingredient in the 3Biome formula is thoroughly inspected to ensure that it is non-GMO, vegan, and gluten-free. Next, we use only non-GMO vegetable capsules to deliver the natural ingredients safely and efficiently inside your body. Finally, we test each finished batch of 3Biome again before the bottles are sealed to ensure that the product is definitively non-GMO, vegan, and gluten-free.

Absolutely not! Auto-Delivery is optional for all of our products.

If you order 3Biome every month, we recommend that you customize your own Auto-Delivery plan for your own convenience. All Auto-Delivery shipments come with free shipping and a full 30 day money back guarantee, no matter how many bottles you order. However, it is not required.

Traditional probiotic supplements typically combine high doses of several different bacteria strains, with the expectation that the vast majority of bacteria cultures will not survive their journey through the digestive tract and into the colon. However, they do not take into consideration how such large quantities of bacteria introduced into an already upset stomach will further exacerbate gastrointestinal distress. Very few, if any, of these combined remedies are clinically tested for safety and effectiveness.

But we designed 3Biome as a combination of the most advanced smart strains of beneficial bacteria, which are naturally protected against the hostile environment of the digestive tract and activate only upon reaching the colon. This allows us to include only the minimum effective dose required to provide comprehensive support for your gut microbiome, avoiding the uncomfortable gastrointestinal side effects of other high-dose probiotics. Each live culture in the 3Biome formula was chosen not only for its own safety and effectiveness, but also its ability to work as a unit with the other strains in the formula.

Princeton Consumer Research conducted a placebo-controlled clinical study with 50 participants to determine 3Biome's effectiveness over the course of 30 days. They found that more than 95% of participants experienced a significant reduction in digestive distress and bowel issues after 30 days of use. 3Biome significantly outperformed placebo in all testing criteria. In addition, none of the participants reported any negative side effects. Click here for the complete results of the study.

In a placebo-controlled clinical study, over 95% of participants taking 3Biome reported significant improvement in their digestive issues and bowel regularity within 30 days of use. Click here for the complete results of the study.

Our customers have confirmed this by giving 3Biome an average rating of 4.5 out of 5 stars. However, please keep in mind that everyone's body is different. The best way to know for sure if 3Biome will work for you is to try it yourself. That's why we offer a 30 Day Money Back Guarantee with every purchase of 3Biome so you can see how it works for you.

3Biome is intended to be taken daily. However, each person is different and may find that they prefer to take 3Biome in different ways for maximum effectiveness.

For daily use, we recommend taking 1 capsule per day to allow the beneficial bacteria to aid in the digestive process and restore balance to the gut microbiome.

For more significant gastrointestinal issues, we recommend taking 1 capsules twice per day to provide maximum strength probiotic support and defense against digestive distress.

Proper dosage is an individual process that depends on what works best for you and your body. We do not recommend taking more than 6 capsules per day.

For most people, we recommend taking 3Biome in the morning approximately 30 minutes before your first meal of the day so that the smart cultures can be efficiently integrated into your gut microbiome. However, it is just as effective to take 3Biome with a meal at lunch or dinner.

You may take 3Biome with or without food. However, please keep in mind that if you take 3Biome with food, it may take longer for the beneficial bacteria cultures to activate when they reach your colon.

3Biome is available online at nutreance.com. We accept all major credit and debit cards including Visa, MasterCard, American Express, and Discover.

3Biome is also available for purchase on amazon.com.

Every page of our website is secured by an SSL certificate issued by Cloudflare, which ensures that any information that you share with us is secured by a cutting-edge 256-bit encryption. In addition, our entire site is scanned daily by McAfee for vulnerabilities and is certified as secure.

Yes, the personal information you disclose to us will remain secure and confidential. We do not and will not under any circumstances share or sell your personal information with any third party. For details, please read our Privacy Policy.

3Biome is not currently available in any physical retail stores. We prefer to provide 3Biome directly to our customers. This way, we can maintain our strict quality control standards throughout production, storage, handling, and shipment until it arrives safely at your door.

We currently offer a Risk-Free 30 Day Supply of 3Biome for $39.95. Every purchase of our 30 Day Supply comes with our 30 Day Money Back Guarantee. We offer free shipping and significant volume discounts for ordering 2 bottles or more. Please visit our order page to find out more.

Yes, you can pay online using all major credit and debit cards including Visa, MasterCard, American Express, and Discover. We do not accept orders by check or money order.

Yes, you can order 3Biome from nearly any country in the world!

Yes, all 3Biome shipments can be delivered to PO Boxes.

We are so confident that 3Biome will work for you that every bottle comes with our 30 Day Money Back Guarantee. If you are not satisfied with your purchase, we don't want you paying for it... even if you have taken the entire bottle! Simply contact us within 30 days of your original purchase, and we will immediately arrange for a refund.

Check out our Return Policy page for more details.

Currently, we ship all orders from the United States, so delivery times depend on the country and region we are shipping to. If you add the product to your cart, you will be able to enter your postal code to compare delivery times and shipping rates specific to your region. That way, you can choose the shipping option that best suits you!

Yes, 3Biome is shipped in discreet packaging that only shows the Nutreance company logo on the outside. On the shipping label, the company name in the return address simply reads "Nutreance."

Please feel free to contact us by e-mail at [email protected] or by phone at to inquire about the status of your order.

Yes, every bottle of 3Biome has a tamper-proof seal on the outside and inside of the cap. In addition, 3Biome is carefully formulated in a GMP-certified, FDA-inspected facility in New York. Please visit our Quality Control page to find out more about the rigorous process that we follow to ensure that every bottle of 3Biome is safe.

3Biome is intended for use by people over the age of 18. If you are not yet 18 years old or if you intend to give 3Biome to someone who is not yet 18 years old, please first consult your pediatrician.

Please consult your doctor before taking 3Biome if you are currently or planning to be pregnant or nursing.

3Biome will not reduce the effectiveness of birth control or interact with contraceptive medication. However, we advise that you talk to your doctor before taking 3Biome or any new supplement.

In general, consumption of moderate amounts of alcohol is safe while taking 3Biome. However, we do not recommend that you consume large quantities of alcohol until you are familiar with how 3Biome affects your body.

In general, 3Biome can be safely taken with antibiotics. However, it is recommended to take 3Biome at least 1 hour before or after a dose of antibiotics to prevent the antibiotic from interfering with the beneficial bacteria in 3Biome. If you are taking any type of antibiotic medication, use caution until you're familiar with the effects of 3Biome. If you are currently taking prescription medication, we advise that you talk to your doctor before taking 3Biome or any new supplement.

In general, 3Biome can be safely taken with antacids, including aluminum hydroxide, calcium carbonate (Alka-Seltzer®, Tums®), magnesium hydroxide (Milk of Magnesia), bismuth subsalicylate (Pepto-Bismol®), Gaviscon®, Gelusil®, Maalox®, Mylanta®, and Rolaids®. If you are taking any type of gastrointestinal medication, use caution until you're familiar with the effects of 3Biome. If you are currently taking prescription medication, we advise that you talk to your doctor before taking 3Biome or any new supplement.

In general, 3Biome can be safely taken with proton pump inhibitors, including omeprazole (Prilosec®), esomeprazole (Nexium®), lansoprazole (Prevacid®), rabeprazole (AcipHex®), pantoprazole (Protonix®), dexlansoprazole (Dexilant®), and zegerid. If you are taking any type of gastrointestinal medication, use caution until you're familiar with the effects of 3Biome. If you are currently taking prescription medication, we advise that you talk to your doctor before taking 3Biome or any new supplement.

If you are currently taking prescription medications, we recommend that you talk with your doctor to ensure that none of the bacteria cultures in 3Biome will interact with your medications. As a natural probiotic, 3Biome is compatible with most prescription medications.

Most 3Biome users do not report experiencing any side effects, as given by the reviews and testimonials that our customers have provided. In the event side effects are experienced, they are most often described as "mild."

Possible side effects from the ingredients in 3Biome include:

• stomach upset
• fever
• sweating
• rash
• diarrhea
• flatulence
• itching
• skin irritation